METAMIZOLE SODIUM VERSUS FENTANYL PLUS METAMIZOLE SODIUM IN ACUTE PAIN TREATMENT AFTER CESAREAN

Abstract

Objective:To evaluate intracutaneo (CI) Fentanyl associated with Metamizole sodium efficacy vs. Metamizole sodium alone in acute pain treatment post-caesarean section. Material and methods: Atransversal-analytical study was made, 100 patients received a single dose of 60 - 90 g fentanyl CI+ 2 g Metamizole sodium in slow intravenous infusion. 100-patient control group underwent only 2 g Metamizole sodium in slow intravenous infusion, three doses in 24 hours. Effects were assessed by direct observation, verbal analog scale, side effect scale, sedation scale and others which evaluate the quality of analgesia. Analysis of items was based on simple frequencies, mean, standard deviation and correlation analysis with Pearson and Spearman correlation coefficient. Results: At Dose and duration of effect correlation was found P<0.01. Fentanyl + Metamizole long lasting relief of pain was between 6 -8 hours in 41.5% of patients compared to the group Metamizole alone, in which 45.5% of patients had pain relief from 2 to 4 hours. Fentanyl CI + Metamizole showed a slight degree of sedation in 38% of patients compared to Metamizole alone that did not have any. Fentanyl CI + Metamizole sodium group showed no major adverse reactions.The use of Fentanyl CI + Metamizole sodium combination is a better choice in acute pain control post-caesarean section.